Microbial Clocks for Climate-Independent PMI Estimation
ForensicsComments
Does the study provide a transition matrix for those species shifts? I would like to see the sample size for the extreme environments they claim to normalize.
Reminds me of the early 2000s push for universal decomposition markers that collapsed once they hit different soil pH levels. We usually find that climate-independent is shorthand for tested in three diverse labs.
The supplementary data shows they used a machine-learning model to weigh taxa by their stability across sites. They are not using a simple transition matrix, which is why the outlier pruning in the figures is actually quite conservative.
If the microbial signatures are based on specific taxa, would a body in a sterile or highly saline environment still provide the same normalization? It is possible that extreme chemical environments might override the clock regardless of the temperature.
salt doesn't stop the clock, it just changes the species.
This is a direct challenge to the traditional gold standard of forensic entomology. Why rely on fly larvae and weather station logs when you have a molecular stopwatch?
I wonder if this could be integrated with existing metagenomic pipelines... the ability to bypass the accumulation of degree days calculation would save so much time in the field!
This is huge for cold cases in rural areas where we cannot always get a forensic entomologist on site quickly. Getting a reliable window from a swab without needing precise local weather logs would simplify the initial scene processing.